The Server.MapPath property maps the specified relative or virtual path to the corresponding physical directory on the server.
protected void Application_Start(Object sender, EventArgs e)
{
StreamReader sr = null;
XmlDocument xmldoc = new XmlDocument();
try
{
sr = new StreamReader(Server.MapPath("./Data/content.xml"));
xmldoc.LoadXml(sr.ReadToEnd());
//.....
}
finally
{
if (sr != null)
{
sr.Close();
}
}
}